EP04.30: Fetal dilated cardiomyopathy: genetic susceptibility?

Genetic Testing for Dilated Cardiomyopathy

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Role of Genetic Factors in Dilated Cardiomyopathy

Genetic Variations Leading to Familial Dilated Cardiomyopathy

Cardiomyopathy is a major cause of death worldwide. Based on pathohistological abnormalities and clinical manifestation, cardiomyopathies are categorized into several groups: hypertrophic, dilated, restricted, arrhythmogenic right ventricular, and unclassified. Dilated cardiomyopathy, which is characterized by dilation of the left ventricle and systolic dysfunction, is the most severe and preva...

Genetic mutations and mechanisms in dilated cardiomyopathy.

Genetic mutations account for a significant percentage of cardiomyopathies, which are a leading cause of congestive heart failure. In hypertrophic cardiomyopathy (HCM), cardiac output is limited by the thickened myocardium through impaired filling and outflow. Mutations in the genes encoding the thick filament components myosin heavy chain and myosin binding protein C (MYH7 and MYBPC3) together...

Genetic polymorphisms in dilated cardiomyopathy Johann